4^th International Conference on Tissue Science and Regenerative Medicine July 27-29, 2015 Rome, Italy

Denis Barritault graduated in Math and Physics, completed his Ph.D. in biochemistry in Paris University. Post doctoral in molecular immunology at Pasteur Institute and NYU as NIH Fogarty Fellow he joined INSERM unit in Paris as developmental biologist. He made the first description and patents of FGF extracted from retina in 1979 and 82 as skin and cornea healing agent, became full professor at Paris East University in 1985, founded and directed a CNRS Laboratory on cell and tissue regeneration until 2003. He is now President of OTR3, Emeritus Professor and author in over 200 publications and 29 patents.

tissue regeneration, molecular immunology

Giorgio Calori Maria has completed his education of Medicine and Surgery University of Milan in 1982; 1987 Specialization School in Orthopaedics and Traumatology University of Milan; 1990 Specialization School in Physical Therapy and Rehabilitation, University of Milan; 1994 Specialization School in Hand Surgery University of Florence. At present working as Chairman of Complex Operative Unit of Orthopaedic Reparative Surgery and Risk Management, G.Pini Orthopaedic Institute, piazza Cardinal Ferrari 1, University of Milan. Also as Professor at the University of Milan at the Graduate School of Orthopaedics and Traumatology and tutor of the course on "Biological processes in the repair of fractures and in nonunions" since 2004. Professor at the University of Milan in the course in Medicine and Surgery of the course on "Human Anatomy” since 2003 and of the course on "Orthopaedics and Traumatology" since 2013. His relation with scientific sociteis as President of the European Society of Tissue Regeneration in Orthopaedics and Trauma (ESTROT.) President overseeing the super-specialist Society for osteosynthesis CIO (Italian Osteosynthesis Club) of the Italian Society of Orthopaedics and Traumatology (SIOT). President overseeing the Lombardy Section SLOTO of Italian Hospital Orthopaedics and Traumatologists. Former President of the Tissue Regeneration Commission of the Italian Society of Orthopaedics and Traumatology (SIOT). Member of the international Advisory Board on biotechnologies and regenerative medicine. President of the National Board for regenerative medicine.

Orthopaedics and Traumatology, Medicine and Surgery, regenerative medicine

Babak Kateb, MD is a neuroscientist with more than 15 years of research experience. His research has been focused on introduction of advance diagnostics and therapeutics into clinical neuroscience in order to rapidly identify and introduce game changing technologies to treat neurological disorders such as brain cancer, Alzheimer’s disease, Parkinson’s disease, brain and spinal disorders. He did his Research fellowship at USC department of neurosurgery and also studied Neuroengineering at USC Ming Hsieh Institute.\\\\r\\\\n\\\\r\\\\nBabak established Society for Brain Mapping and Therapeutics (SBMT) while doing his fellowship 13 years ago at USC. Currently, he is the founding chairman of the board of directors & CEO Society for Brain Mapping and Therapeutics (SBMT), President and Scientific Director of the Brain Mapping Foundation and Director of National Center for Nano-Bio-Electronics.; the center is focused on integration of nanotechnology, cellular therapeutics/stem cell, medical device and imaging. He was Director of Research and Development at the Department of Neurosurgery at City of Hope Cancer Center. He is also Research Scientist at Department of Neurosurgery at Cedars Sinai Medical center. He is recipient of NASA Tech Brief Award for his pioneering work on sniffing cancer cells using NASA’s electronic nose. He has pioneered the technique for using NASA Multiwall carbon nanotubes to activate macrophages for brain cancer immunotherapy and recently has received an approval from the FDA to microwave soft tissue. The technology also could be used for brain, liver, head and neck, prostate and breast cancer. \\\\r\\\\nIn 2015 Society for Brain Mapping and Therapeutics and Brain Mapping Foundation Board of Directors presented him with Pioneer in Medicine award. He has been recognized by Mayor of Los Angeles and Governor of California for his dedication in science. He is currently collaborating with Los Alamos National Lab and has duel appointment with NASA/JPL as a visiting scientist. His research at NASA and LANL involves the use of Artificial Intelligence and Supercomputing for Brain Mapping and therapeutics, use of electronic nose for cancer detection, application of new UV imaging for intraoperative brain mapping and use of LANL advance ultrasonic technology for brain stimulation; Babak has many patents in these areas. \\\\r\\\\n\\\\r\\\\nHe has established a new publication with PLoSOne, which is called PLoSOne_ NeuroMapping & Therapeutics, which he serves as editor in chief and was the force behind 3 successful NeuroImage-Brain Mapping and Therapeutics special issues. He is editor of The inaugural Textbook of Nanoneuroscience and Nanoneurosurgery, published by, Taylor & Francis 2013 and the editor of the inaugural textbook of Neurophotonic and Brain Mapping, which is due for a release for Dec. 2015. \\\\r\\\\n\\\\r\\\\nHe has been deeply involved in global neuroscience legislation through his close collaboration with the US Congressional Neuroscience Caucus as well as members of Canadian Parliaments. He has chaired 3 congressional briefing on Brain Mapping and given a talk to the Canadian Parliament. His initiatives have impacted the health care delivery to the wounded soldiers in the US. He has been one of the key players in President Obama’s BRAIN initiative and co-author of the G20 World Brain Mapping and Therapeutics Initiative and African Brain Mapping Initiative. He is also 13 times Marathon runner.

Introduction of advance diagnostics and therapeutics into clinical neuroscience in order to rapidly identify and introduce game changing technologies to treat neurological disorders such as brain cancer, Alzheimer’s disease, Parkinson’s disease, brain and spinal disorders.

Giacomo Cao, Professor of Chemical Engineering, is currently the Coordinator of the Ph.D. Program in Biomedical Engineering at the University of Cagliari, Italy and the Head of the Bioengineering Group at CRS4, Italy. The main research interests in the field of biomedical engineering are the design of rotating bioreactors for engineered cartilage growth, the experimental analysis and modeling of in vitro proliferation of mesenchymal stem cells, the use of human mesenchymal stem cells for acute toxicity tests as well as the development of novel processes for tissues decellularization and recellularization.

Bioengineering, mesenchymal stem cells, tissues decellularization, recellularization

Joseph Purita is Director of Institute of Regenerative and Molecular Orthopedics (www.stemcellorthopedic.com) in Boca Raton, Florida. The Institute specializes in the use of Stem Cells and Platelet Rich Plasma injections. Dr. Purita is a pioneer in the use of Stem Cells and Platelet Rich Plasma. The Institute has treated some of the most prominent professional athletes from all major sports in both the U.S.A. and abroad. He received a B.S. and MD degree from Georgetown Univ. Dr. Purita is board certified in Orthopedics by ABOS. He is a Fellow American College of Surgeons, Fellow American Academy Orthopedic Surgeons, and a Fellow American Academy of Pain Management. He is also certified in Age Management Medicine. He has lectured and taught extensively throughout the world on the use of Stem Cells and Platelet Rich Plasma. He has been instrumental in helping other countries in the world establish guidelines for the use of Stem Cells in their countries. He has been invited to lecture on these techniques throughout the world as a visiting professor.

Molecular Orthopedics, Pain Management

Gordon Blunn is a bioengineer at the Institute of Orthopaedics and Musculoskeletal Science at University College London; he is based at the Royal National Orthopaedic Hospital. He has been at this Institution for 25 years and during this period of time he has investigated the use of the fixation of implants to the skeleton. He has translated a number of novel treatments and designs into patients, which has enhanced implant fixation. He is currently the president of the British Orthopaedic Research Society. Over the last 5 years he has secured in excess of £3.6 million in funding, holds the position of Chief Scientific Officer for Stanmore Implants Worldwide Ltd. and is co-director of the London Implant Retrieval Centre (LIRC). He has extensive research experience in orthopaedic medical devices, materials and musculoskeletal tissues. A number of his research projects have been translated into clinical practice. He has worked on the reattachment of tendons to bone and to implant surfaces, the integration of implants with the skeleton, the wear of implant bearing materials and the use of bone graft substitute materials. Recently his research has focused on the design and development of implants, retrieval analysis and reconstruction of bone and joints. He has published over 150 papers in peer-reviewed journals; holds a number of patents on medical devices as well as being a scientific advisor to a number of SMEs.

orthopaedic medical devices, materials and musculoskeletal tissues

Dennis Lox practices Sports and Regenerative Medicine in the Tampa Bay, Florida and the Washington D.C. metro areas in the United States. Dr. Lox has treated numerous patients with AVN. As well as patients from all levels of sports competition including the professional ranks. Dr.Lox frequently presents his findings at national and International Conferences on Regenerative Medicine and Tissue Engineering.

Regenerative Medicine, sports medicine, musculoskeletal regeneration

Jan O. Gordeladze, Ph.D. (born 24th of April, 1950), holds a triple professor competence (medical biochemistry, physiology, and pharmacology), and is presently working as a professor at the Department of Biochemistry, Institute of Basic Medical Science, University of Oslo, Norway. He has previously been employed as the medical director of MSD, Norway, serving two years as a Fulbright scholar at the NIH, Bethesda, Maryland, USA, and from 2006-2009 being employed as associate professor at the University of Montpellier, France. He has published more than 100 scientific articles, reviews/book chapters and presented more than 250 abstracts/posters/talks at conferences world wide.

Biochemistry, medical biochemistry, tissue engineering, pharmacology

Kristin Comella has over 15 years’ experience in corporate entities with expertise in regenerative medicine. She was recently named number 24 according to Terrapin’s list of the Top 50 Global Stem Cell Influencers. Ms. Comella has pioneered a variety of stem cell therapies including cord blood derived cells, bone marrow cells, muscle cells and adipose cells for use in many different applications. She has developed a wide range of regenerative products and techniques that have been successfully implemented into the clinic. She also led the team that gained the first ever FDA approval for clinical trials using a combined cell and gene therapy product. Ms. Comella has been a member of the Bioheart Inc. senior management team since 2004 and is currently serving as the Chief Scientific Officer and board member. Bioheart is a publically traded company focusing on the discovery, development and commercialization of autologous cell therapies for the treatment of degenerative diseases. Since joining Bioheart, she has played a major role in managing the product development, manufacturing and quality systems of cellular products. In addition, Ms. Comella is currently and actively serving on multiple boards in the stem cell arena. She was co-founder and Chief Executive Officer of Stemlogix, LLC for veterinary medicine. Ms. Comella has years of cell culturing experience including building and managing the stem cell laboratory at Tulane University's Center for Gene Therapy. Previously, she worked as a research engineer for Osiris Therapeutics developing stem cell therapies for osteoarthritis. Ms. Comella holds an M.S. in Chemical Engineering from The Ohio State University and a B.S. in Chemical Engineering from the University of South Florida.

Ion N. Mihailescu is Senior Scientific Researcher 1st degree in LSPI – INFLPR and Professor and PhD supervisor at Physics Department, University of Bucharest. Current fields are biophysics and biomedicine; plasma and laser physics and theory and current research interests go to surface studies with lasers; surface processing; deposition and modification of thin solid structures by high intensity laser irradiation; and biomaterials. He received the 1994 Galileo Galilei Award of the International Commission for Optics (ICO) “for outstanding contributions to the field of optics". He authored more than 400 publications, Hirsch index 27, total citations over 3000.

biophysics, biomedicine, laser physics, biomaterials

Peter trained at Cambridge University under the supervision of the co-inventor of IVF and Nobel Laureate Professor Sir Bob Edwards FRS. His PhD was in stem cell technology. His post-doctoral position was as a Senior Embryologist at Bourn Hall Clinic which was the first IVF clinic in the world. Peter has been the Scientific Director of Cells for Life in Toronto and Smart Cells in the UK and was HTA Designated Individual for Smart Cells. He has carried out research in stem cell technology and has written numerous papers and book chapters on stem cell technology. He has been an invited speaker to many international conferences including personal invitations to speak twice at the Vatican, the UK House of Lords and The Canadian Parliament. Peter also has experience in creating new stem cell technology labs and the related accreditation and regulatory aspects of stem cell labs. Peter is currently developing a new stem cell laboratory for Wide Cells Ltd at the University of Manchester Innovation Centre. He is currently the Chief Scientific Officer of Wide Cells Ltd and Dean of Wide Academy.

stem cell technology

Prakash Kulkarni studies living systems which are dynamical systems, and employs both theoretical as well as experimental approaches. His research that is focused on intrinsically disordered proteins, integrates interdisciplinary approaches from fields as varied as biology, bioengineering, physics, structural biology, computational biology, and mathematics to answer important questions such as state or phenotypic switching, self-organization, synchronization, and evolution that have important biological and biomedical implications. He uses cancer as a model system. Kulkarni obtained a Ph.D in biochemistry from India and did his postdoctoral training in cell biology at New York University. Subsequently, he worked in the Division of Chemistry & Chemical Engineering at the California Institute of Technology, and in the Department of Genetics at Yale University. He is currently an Associate Professor at the Institute for Bioscience & Biotechnology Research at the University of Maryland. Previously, he was an Assistant Professor of Urology, in the James Buchanan Brady Urological Institute and Oncology at the Sidney Kimmel Cancer Center, Johns Hopkins University, and from 2010-2012, he was the Irene and Bernard L. Schwartz Scholar of the Patrick C Walsh Prostate Research Fund.

bioengineering, structural biology, computational biology, biomedical implications

Paolo Ferruti was born in Milan, Italy, on June 5, 1938. He took his degrees of Chemistry by Oct., 1963 at the historical prestigious college (“Almo Collegio Borromeo”) of Pavia, Italy. Immediately afterwards Nobel Prize Giulio Natta summoned him as researcher at the Industrial Chemistry Dept of the Polytechnic of Milan where he got a permanent position as Assistant Professor in 1964. In 1968 he went on leave to the University of California, Berkeley where he collaborated with Nobel Prize Melvin Calvin at the Lawrence Radiation Laboratory. In 1975 he was summoned as Full Professor of Industrial Chemistry at the University of Naples and subsequently commuted with the same academic position to the Universities of Bologna (1979-1984), Brescia (1984-1995) and finally Milan (1995-2010). In 2010 he retired from teaching in compliance with Italian regulations, but is still an official guest of the University of Milan very actively doing research with his former research group at the Department of Chemistry. Professor Ferruti is credited to be the inventor of polyamidoamines, a polymer family whose interest is steadily increasing, having published the first papers on them between the late sixties and early seventies of the last century. He authored to date more than 300 papers and 50 patents, mostly on polyamidoamines, but also on other functional polymers for technical and biotechnological applications, such as functionalized poly-4-acryloylmorpholine (PACM), PEG and PVP, as well as on  and -cyclodextrin-based soluble polymers and pH-sensitive crosslinked nanosponges.

Roberta Di Pietro got the degree in Medicine cum Laude in 1985 and the PhD in Sports Medicine cum Laude in 1988, University of Chieti, Italy. She worked as a visiting scientist in UK at the Biochemistry Department, AFRC, Cambridge; in USA at the Pathology Department, USUHS, Bethesda, and at the Institute of Human Virology, University of Maryland, Baltimore. She currently works at the G. d’Annunzio University of Chieti, Italy, as a Full Professor of Histology. She joined the Editorial Board of Current Pharmaceutical Design as an Executive Guest Editor and since 2010 she was recognized as a Registered Referee for Archives of Ophthalmological Reviews and Reproductive Biology and Endocrinology. She is now author of 168 scientific publications plus international e-bookchapters and Italian textbooks.

Sports Medicine, Histology

Anand Ramamurthi, Ph.D. is Associate Professor of Biomedical engineering at the Cleveland Clinic with adjunct appointments at Case Western Reserve University, and Clemson University, where he was earlier a tenured faculty. He received a doctorate from Oklahoma State University and was an AHA postdoctoral fellow at the Cleveland Clinic. He directs a well-funded research program focused on biomimetic regenerative repair of ECM/elastic matrix, in vitro, and at sites of proteolytic disease. Anand is a member of several vascular disease-related professional societies and their committees, and an editorial-board member of repute in the JTSE. He is a peer-reviewer for several funding agencies and 20+ journals, and has 38 peer-reviewed publications.

biomimetic regenerative repair, elastic matrix, vascular disease, Biomedical engineering

Shuanhu Zhou, Ph.D. is an Associate Scientist at Brigham and Women's Hospital and Assistant Professor at Harvard Medical School. Dr. Zhou received his B.S. degree from Sichuan University, China and Ph.D. from Hebrew University of Jerusalem, Israel, and had his postdoctoral training in Harvard University, USA. Dr. Zhou has published more than 60 peer-reviewed papers and book chapters, and served as an evaluation expert for journals and organizations. He received several awards, including 2001 Rector Award of Hebrew University for excellent Ph.D. student and 2006 John Haddad Young Investigator Award from American Society for Bone and Mineral Research.

His research interest s on commitment an academic research career in the field of biogerontology and orthopedic science, focusing on adult stem cells, their niche and skeletal aging.

Nelson R. Pinto: University of the Andes, Faculty of Dentistry, Santiago, CHILE. Visiting Professor, Department of Oral HealthSciences / Periodontology , University Hospitals, Catholic University Leuven, BELGIUM. Founder and Chairman of the Research Center of Regenerative Medicine and Tissue Engineering, Concepción, CHILE. Clinical Editor POSEIDO JOURNAL. World Leader on Clinical Applications of L-PRF in Hard and Soft Tissue Regeneration and Wound Healing. Developer of the Technique for the Treatment of Chronic Wounds with L-PRF. (Best Oral Research Presentation: 4th Congress of the World Union of Wound Healing Societies, Yokohama, Japan, 2012) National and International Lecturer on Implant Dentistry and Regenerative Medicine.

Regenerative Medicine, Tissue Regeneration, Wound Healing, Implant Dentistry