Bone and Cartilage Tissue Engineering

Tissue engineering of musculoskeletal tissues, particularly bone and cartilage, is a rapidly advancing field. In bone, technology has centred on bone graft substitute materials and the development of biodegradable scaffolds. Recently, tissue engineering strategies have included cell and gene therapy. The availability of growth factors and the expanding knowledge base concerning the bone regeneration with modern techniques like recombinant signalling molecules, solid free form fabrication of scaffolds, synthetic cartilage, Electrochemical deposition, spinal fusion and ossification are new generated techniques for tissue-engineering applications. The worldwide market for bone and cartilage repairs strategies is estimated about $300 million. During the last 10/15 years, the scientific community witnessed and reported the appearance of several sources of stem cells with both osteon and chondrogenic potential. Several sessions on tissue engineering like bone tissue engineering meetings, biomaterials meetings, implants meetings, cartilage regeneration symposiums are being conducted on a large scale every year.

  • Principles of Bone and Cartilage Reconstruction
  • Cell sources for bone and cartilage tissue engineering
  • Osteogenic signaling factors
  • Chondrogenic signaling factors
  • Design and fabrication of 3-D scaffold
  • Using stem cells to build new bones

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