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8th International Conference on Tissue Science and Regenerative Medicine, will be organized around the theme “Explore and Exploit the Novel Techniques to Repair, Restore and Regenerate”
Tissue Science Congress is comprised of keynote and speakers sessions on latest cutting edge research designed to offer comprehensive global discussions that address current issues in Tissue Science Congress
Submit your abstract to any of the mentioned tracks.
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Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological tissues. Tissue engineering involves the use of a scaffold for the formation of new viable tissue for a medical purpose. While it was once categorized as a sub-field of biomaterials, having grown in scope and importance it can be considered as a field in its own. While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, skin, muscle etc.). Often, the tissues involved require certain mechanical and structural properties for proper functioning. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bio artificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells or progenitor cells to produce tissues.
- Track 1-1Musculoskeletal tissue regeneration
- Track 1-2Cardiovascular tissue regeneration
- Track 1-3In-situ tissue regeneration
- Track 1-4Tissue biomarkers
- Track 1-5 Tissue graft tolerance
- Track 1-6Tissue mechanics and mechanobiology
Tissue repair and regeneration following injury or disease are often thought to recapitulate embryonic development by using similar molecular and cellular pathways. In addition, many embryonic tissues, such as the spinal cord, heart, and limbs, have some regenerative potential and may utilize mechanisms that can be exogenously activated in adult tissues. For example, BMP signalling regulates nervous system development, and SMAD reactivation plays a critical role in adult nerve regeneration and repair in animal models of spinal cord injury. While similar molecular pathways are utilized during embryogenesis and adult tissue regeneration, recent reports suggest the mechanisms by which these developmental programs are reactivated and maintained may vary in adult tissues. Adult fish and amphibians have a remarkable capacity for tissue regeneration, while mammals have a limited regenerative capacity.
- Track 2-1Dental tissue repair
- Track 2-2Deregulation of normal tissue repair
- Track 2-3Effects of guided tissue regeneration
- Track 2-4Organ-Specific Regeneration
- Track 2-5Cancer, Skin, and the Wound Healing Analogy
- Track 2-6Epigenetics
Stem cells are undifferentiated cells, which can differentiate into specialized cells and can divide to produce more stem cells. They are found in multicellular organisms. In mammals, there are two broad types of stem cells: embryonic stem cells, which are isolated from the inner cell mass of blastocysts, and adult stem cells, which are found in various tissues. In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing adult tissues. In a developing embryo, stem cells can differentiate into all the specialized cells—ectoderm, endoderm and mesoderm - but also maintain the normal turnover of regenerative organs, such as blood, skin, or intestinal tissues.
- Track 3-1Single-step stem cell-based knee repair
- Track 3-2Restoring blood flow with stem cells
- Track 3-3 Repairing the nervous system with stem cells
- Track 3-4Intellectual property of human pluripotent stem cells
- Track 3-5Mending a broken heart: Cardiac repair
- Track 3-6Neural Stem Cell Therapy
Biomaterials and Bioengineering play a pivotal role in field of tissue engineering. Biomimetic synthetic polymers have been created to elicit specific cellular functions and to direct cell-cell interactions both in implants that are initially cell-free, which may serve as matrices to conduct tissue regeneration, and in implants to support cell transplantation. Biomimetic approaches have been based on polymers endowed with bioadhesive receptor-binding peptides and mono- and oligosaccharides. These materials have been patterned in two- and three-dimensions to generate model multicellular tissue architectures, and this approach may be useful in future efforts to generate complex organizations of multiple cell types.
- Track 4-1Myocardial tissue engineering
- Track 4-2Orthopedic and musculoskeletal medicines
- Track 4-3Strategies for skin tissue regeneration
- Track 4-4Drug eluting stents
In biology, regeneration is the process of renewal, restoration, and growth that makes genomes, cells, organisms, and ecosystems resilient to natural fluctuations or events that cause disturbance or damage. Every species is capable of regeneration, from bacteria to humans. Regeneration can either be complete where the new tissue is the same as the lost tissue, or incomplete where after the necrotic tissue comes fibrosis. At its most elementary level, regeneration is mediated by the molecular processes of gene regulation. Regeneration in biology, however, mainly refers to the morphogenic processes that characterize the phenotypic plasticity of traits allowing multi-cellular organisms to repair and maintain the integrity of their physiological and morphological states. Above the genetic level, regeneration is fundamentally regulated by asexual cellular processes. Regeneration is different from reproduction. For example, hydra performs regeneration but reproduce by the method of budding.
- Track 5-1Medical Devices and Artificial Organs
- Track 5-2Cellular Therapies
- Track 5-3Regenerating a new kidney
- Track 5-4Clinical Translation
Stem cells are undifferentiated cells, that can differentiate into specialized cells and can divide to produce more stem cells. They are found in multicellular organisms. In mammals, there are two broad types of stem cells: embryonic stem cells, which are isolated from the inner cell mass of blastocysts, and adult stem cells, which are found in various tissues. In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing adult tissues. In a developing embryo, stem cells can differentiate into all the specialized cells—ectoderm, endoderm and mesoderm - but also maintain the normal turnover of regenerative organs, such as blood, skin, or intestinal tissues.
- Track 6-1Embryonic stem (ES) cells
- Track 6-2 Adult stem cell
- Track 6-3Induced Pluripotent Stem Cells
- Track 6-4Tissue stem cells
- Track 6-5Application of stem cell
Scaffolds are one of the three most important elements constituting the basic concept of regenerative medicine, and are included in the core technology of regenerative medicine. Every day thousands of surgical procedures are performed to replace or repair tissue that has been damaged through disease or trauma. The developing field of tissue engineering (TE) aims to regenerate damaged tissues by combining cells from the body with highly porous scaffold biomaterials, which act as templates for tissue regeneration, to guide the growth of new tissue. Scaffolds has a prominent role in tissue regeneration the designs, fabrication, 3D models, surface ligands and molecular architecture, nanoparticle-cell interactions and porous of the scaffolds are been used in the field in attempts to regenerate different tissues and organs in the body. The world stem cell market was approximately 2.715 billion dollars in 2010, and with a growth rate of 16.8% annually, a market of 6.877 billion dollars will be formed in 2016. From 2017, the expected annual growth rate is 10.6%, which would expand the market to 11.38 billion dollars by 2021. Several scaffolds workshops, bioreactors workshops are being conducted globally. Together with biomaterials, stem cell technology is also being used to improve the existing healthcare facilities. These concepts and technologies are being used for the treatment of different diseases like cardiac failure, fractures, deep skin injuries, etc. Introduction of nanomaterials on the other hand is becoming a big hope for a better and an affordable healthcare.
- Track 7-1Scaffold designs
- Track 7-2Fabrication of scaffolds
- Track 7-3Biodegradable nanofiber scaffolds
- Track 7-4D scaffolds and models
- Track 7-5Surface ligands and molecular architecture
- Track 7-6Porous scaffolds
Stem cell transplantation is a procedure that is most often recommended as a treatment option for people with leukaemia, multiple myeloma, and some types of lymphoma. It may also be used to treat some genetic diseases that involve the blood. During a stem cell transplant diseased bone marrow (the spongy, fatty tissue found inside larger bones) is destroyed with chemotherapy and/or radiation therapy and then replaced with highly specialized stem cells that develop into healthy bone marrow. Although this procedure used to be referred to as a bone marrow transplant, today it is more commonly called a stem cell transplant because it is stem cells in the blood that are typically being transplanted, not the actual bone marrow tissue.
- Track 8-1Autologous stem cell transplant
- Track 8-2Cord blood stem cell transplant
- Track 8-3Embryonic stem cell transplant
- Track 8-4Hematopoietic stem cell transplantation
Tissue culture, a method of biological research in which fragments of tissue from an animal or plant are transferred to an artificial environment in which they can continue to survive and function. The cultured tissue may consist of a single cell, a population of cells, or a whole or part of an organ. Cells in culture may multiply; change size, form, or function; exhibit specialized activity (muscle cells, for example, may contract); or interact with other cells.
- Track 9-1Plant tissue culture
- Track 9-2Animal tissue culture
- Track 9-3Tissue culture techniques
- Track 9-4Application of tissue culture
Translational science is a multidisciplinary form of science that bridges the recalcitrant gaps that sometimes exist between fundamental science and applied science, necessitating something in between to translate knowledge into applications. The term is most often used in the health sciences and refers to the translation of bench science, conducted only in a lab, to bedside clinical practice or dissemination to population-based community interventions. Translational Medicines: Translational medicine, also called translational medical science, preclinical research, evidence-based research, or disease-targeted research, area of research that aims to improve human health and longevity by determining the relevance to human disease of novel discoveries in the biological sciences.
- Track 10-1Biomarkers in Translational Medicine
- Track 10-2Data Management and Data Mining Approaches
- Track 10-3Drug Development Process
- Track 10-4Case Studies and Reports
Stem-cell therapy is the use of stem cells to treat or prevent a disease or condition. Bone marrow transplant is the most widely used stem-cell therapy, but some therapies derived from umbilical cord blood are also in use. Research is underway to develop various sources for stem cells, and to apply stem-cell treatments for neurodegenerative diseases and conditions such as diabetes, heart disease, and other conditions. Stem-cell therapy has become controversial following developments such as the ability of scientists to isolate and culture embryonic stem cells, to create stem cells using somatic cell nuclear transfer and their use of techniques to create induced pluripotent stem cells. This controversy is often related to abortion politics and to human cloning. Additionally, efforts to market treatments based on transplant of stored umbilical cord blood have been controversial.
- Track 11-1Development of regenerative treatment models
- Track 11-2 Sources of stem cells
- Track 11-3 Stem cells and hard-tissue repair
- Track 11-4Stem cells and orthopedic repairs
- Track 11-5Application of stem cell therapy
There are more than 200 types of cancer, including Breast cancer, skin cancer, lung cancer, colon cancer, Prostate cancer, and lymphoma. Symptoms and Treatment varies depending on the type of Cancer. Some people with cancer will have only one treatment. But most people have a combination of treatments, such as surgery with chemotherapy and/or radiation therapy. The Anticancer therapies include Surgical therapy, Chemotherapy, Adjuvant therapy, Neoadjuvant therapy, Palliative therapy, Immunotherapy, Hormonal therapy, Radiotherapy, Nutritional therapy, Phototherapy. Phototherapy / proton beam therapy is the most advanced among all the therapies. All Anticancer agents act by disturbing cell multiplication or normal functioning, DNA synthesis or chromosomal migration, and by blocking or changing RNA and protein metabolism.
- Track 12-1Surgical Therapy
- Track 12-2Chemotherapy
- Track 12-3Radiation Therapy
- Track 12-4Cancer Genetics
- Track 12-5Cancer Immunotherapy
Tissue engineering of musculoskeletal tissues, particularly bone and cartilage, is a rapidly advancing field. In bone, technology has centred on bone graft substitute materials and the development of biodegradable scaffolds. Recently, tissue engineering strategies have included cell and gene therapy. The availability of growth factors and the expanding knowledge base concerning the bone regeneration with modern techniques like recombinant signalling molecules, solid free form fabrication of scaffolds, synthetic cartilage, Electrochemical deposition, spinal fusion and ossification are new generated techniques for tissue-engineering applications. The worldwide market for bone and cartilage repairs strategies is estimated about $300 million. During the last 10/15 years, the scientific community witnessed and reported the appearance of several sources of stem cells with both osteon and chondrogenic potential. Several sessions on tissue engineering like bone tissue engineering meetings, biomaterials meetings, implants meetings, cartilage regeneration symposiums are being conducted on a large scale every year.
- Track 13-1 Principles of Bone and Cartilage Reconstruction
- Track 13-2Cell sources for bone and cartilage tissue engineering
- Track 13-3Osteogenic signaling factors
- Track 13-4 Chondrogenic signaling factors
- Track 13-5Design and fabrication of 3-D scaffold
- Track 13-6Using stem cells to build new bones
Aging is an accumulation of damage to macromolecules, cells, tissues and organs. If any of that damage can be repaired, the result is rejuvenation. There are at least eight important hormones that decline with age: 1. human growth hormone (HGH); 2. the sexual hormones: testosterone or oestrogen/progesterone; 3. erythropoietin (EPO); 4. insulin; 5. DHEA; 6. melatonin; 7. thyroid; 8. pregnenolone. In theory, if all or some of these hormones are replaced, the body will respond to them as it did when it was younger, thus repairing and restoring many body functions. In line with this, recent experiments show that heterochronic parabiosis, i.e. connecting the circulatory systems of young and old animal, leads to the rejuvenation of the old animal, including restoration of proper stem cell function. Stem cell regenerative medicine uses three different strategies: 1) Implantation of stem cells from culture into an existing tissue structure, 2) Implantation of stem cells into a tissue scaffold that guides restoration, 3) Induction of residual cells of a tissue structure to regenerate the necessary body part.
- Track 14-1PQQ: Reverse Cellular Aging
- Track 14-2Protection Against Brain Aging
- Track 14-3Stem Cell Therapies Produce Rejuvenation
- Track 14-4Applications of Rejuvenation
An irregular mass of tissue, tumours are a great indication of aggravation, and can be favourable or threatening. Tumour for the most part mirror the sort of tissue they emerge in. Treatment is likewise particular to the area and kind of the tumour. Benevolent tumours can once in a while essentially be overlooked, destructive tumours; choices incorporate chemotherapy, radiation, and surgery.
Some parts of our bodies can repair themselves quite well after injury, but others don’t repair at all. We certainly can’t regrow a whole leg or arm, but some animals can regrow - or regenerate - whole body parts. Regeneration means the regrowth of a damaged or missing organ part from the remaining tissue. As adults, humans can regenerate some organs, such as the liver. If part of the liver is lost by disease or injury, the liver grows back to its original size, though not its original shape. And our skin is constantly being renewed and repaired. Unfortunately many other human tissues don’t regenerate, and a goal in regenerative medicine is to find ways to kick-start tissue regeneration in the body, or to engineer replacement tissues.
Gene therapy aims to transfer genetic material into cells to provide them with new functions. A gene transfer agent has to be safe, capable of expressing the desired gene for a sustained period of time in a sufficiently large population of cells to produce a biological effect. Identifying a gene transfer tool that meets all of these criteria has proven to be a difficult objective. Viral and nonviral vectors, in vivo, ex vivo and in situ strategies co-exist at present, although ex vivo lenti-or retroviral vectors are presently the most popular.Natural stem cells (from embryonic, hematopoietic, mesenchymal, or adult tissues) or induced progenitor stem (iPS) cells can be modified by gene therapy for use in regenerative medicine.
- Track 17-1In-vivo gene transfer
- Track 17-2Ex-vivo gene transfer
- Track 17-3Gene doping
- Track 17-4Application of gene therapy
- Track 17-5Allogeneic Cell Therapy
- Track 17-6Human embryonic stem cells
- Track 17-7Mesenchymal Stem Cell Therapy
There are strong pricing pressures from public healthcare payers globally as Governments try to reduce budget deficits. Regenerative medicine could potentially save public health bodies money by reducing the need for long-term care and reducing associated disorders, with potential benefits for the world economy as a whole. The global market for tissue engineering and regeneration products reached $55.9 billion in 2010, is expected to reach $59.8 billion by 2011, and will further grow to $89.7 billion by 2016 at a compounded annual growth rate (CAGR) of 8.4%. It grows to $135 billion to 2024.
- Track 18-1Regenerative medicine research in World
- Track 18-2Human Tissue Market in Asia
- Track 18-3Tissue analysis products Market in USA
- Track 18-4Stem cell analysis products Market in UK